Cooke , an internationally known BMT physician and expert in transplant-related complications including graft-versus-host-disease and acute and chronic lung dysfunction. He has been successful in developing multi-center, translational research protocols in these areas. The Pediatric BMT Program provides transplantation of hematopoietic or blood stem cells derived from the bone marrow as a treatment option for a variety of acquired and congenital disorders of children and young adults, including:.
At Johns Hopkins, BMT patients are managed by an integrated team made up of specialized physicians, nurse practitioners, physician assistants, social workers, and inpatient and outpatient nurses.
Outpatient care is provided in a state-of-the-art clinic located on the same floor as the inpatient unit. The program has significant experience using a variety of conditioning regimens - including both full intensity myeloablative and reduced intensity - to prepare the body for BMT and infuse stem cells from sources including the bone marrow, peripheral blood and cord blood or placenta.
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High dose chemotherapy followed by the infusion of stem cells collected and frozen from the patient is also an option available for many solid tumors, as is high dose cyclophosphamide therapy alone for select bone marrow failure and autoimmune syndromes. Taking care of transplant patients is one of the most complicated and yet rewarding areas of medicine, Dr.
The procedure itself is rather straightforward, but the provision of post-transplant care in the days, weeks, months and years that follow absolutely requires a dedicated, well-trained group of practitioners. Rick Jones. The combined programs received FACT re-accreditation in December of and share a common stem cell processing facility, meetings to discuss relevant patient issues, and clinical protocols, along with infrastructure and resources for clinical trial development, data collection and data monitoring. Request your next appointment through My Chart! Share full text access.
What is the Pediatric Blood and Marrow Transplant Program?
Please review our Terms and Conditions of Use and check box below to share full-text version of article. Abstract Objective To analyze the development of psychopathology in recipients along with their donor and nondonor siblings and the relationship with the bone marrow transplantation BMT process. Methods All children were interviewed using the Kiddie Schedule for Affective Disorders and Schizophrenia to assess psychopathology.
Results In this study, the depressive symptom level was found significantly higher in the donor group compared with the nondonor group. Conclusion Physicians should deal with the family as a whole, not just their patient, and should be aware of the psychiatric risk of other siblings during the assessment. Supporting Information Filename Description ponsupT1.source url
Pediatric Bone Marrow Transplant and Cellular Therapy Program
Early View Online Version of Record before inclusion in an issue. Related Information. Close Figure Viewer. Browse All Figures Return to Figure. Previous Figure Next Figure. Email or Customer ID. Allogeneic transplant — If a child is to receive an allogeneic transplant, this means he or she is getting stem cells from either a family member or an unrelated donor. S and can only be administered by certain certified providers such as Cleveland Clinic Children's. The typical BMT process is laid out below. Pre-Transplant Several important steps take place long before the transplant occurs.
Finding a donor : The medical team will look for a relative, or a donor from the National Marrow Donor Program or cord blood registries. With certain diseases, we may utilize your own bone marrow for the transplant.
Pediatric Blood & Marrow Transplant | Floating Hospital for Children
Pre - transplant evaluation : Before the BMT process begins, your child will need to have an extensive evaluation to determine his or her eligibility for transplant. This evaluation will happen over several visits and includes lab testing, imaging, and consults with other services. Harvesting stem cells : Once a donor is identified, stem cells are harvested.
If the donor is a relative, our team will meet with them separately to review the donation process. Transplant day Day 0 : During the transplant day, stem cells that have been previously collected are given to the patient.
Becoming a Bone Marrow Donor Patients all over the world facing bone marrow transplant procedure need people like you to become a bone marrow donor, to donate blood stem cells or cord blood, or to help in other ways. Ilia Buhtoiarov, MD. Seth Rotz, MD. Kate Eshleman, PsyD. Kathy Bielek, CNP.
Pediatric Blood and Marrow Transplant Program
Kamala Neff, CNP. Julie Pettee, CNP. USA: Patient Stories. Read Story.